Say scientists who have found that puzzles are better for the brain than vitamins or workouts. A study looked at 32 trials involving 25,000 healthy patients aged 65 or older. Studies of drugs, hormone therapy, vitamins and supplements ginkgo, omega 3 and dehydroepiandrosterone (DHEA) showed no positive effect with the evidence of the benefits of physical activity being weak only mental training showed benefits every time. Perhaps all those Sudoku puzzles I do, are not wasted time after all.